Microbiology and Pathology Quiz 10

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Question 1 of 20

1. Question

Each of the following endocrine disorders can contribute to secondary hypertension EXCEPT:

Cushing syndrome.
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Diabetes
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Pheochromocytoma
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Hypoaldosteronism
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Hyperthyroidism
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Question 2 of 20

2. Question

Which bacteria is implicated in more than 50% of all cases of subacute bacterial endocarditis, particularly in patients with pre-existing cardiac valvular damage, often originating from an oral source?

Streptococcus viridans
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Staphylococcus epidermidis
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Staphylococcus aureus
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Streptococcus sanguis
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Streptococcus mutans
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Question 3 of 20

3. Question

Regarding different types of endocarditis, each of the following statements is true EXCEPT:

Libman-Sacks form of endocarditis is caused by intrinsic bacteremia.
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Dental seeding and intravenous drug use cause the infective form.
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The mitral valve is most often affected in the Libman-Sacks form.
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The rheumatic form occurs in areas of greatest hemodynamic stress.
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The mitral valve is most often affected in rheumatic form.
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Question 4 of 20

4. Question

The specific accumulation of serous fluid within the pericardial space is referred to as:

Hemopericardium
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Acute pericarditis.
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Constrictive pericarditis
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Hydropericardium
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Myocarditis
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Question 5 of 20

5. Question

Splinter hemorrhages found under a patient’s fingernails, potentially accompanied by fever, night sweats, and heart murmurs, are clinically indicative of:

Cardiac tamponade
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Endocarditis
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Primary hypertension
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Coronary artery disease
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Angina
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Question 6 of 20

6. Question

Which of the following statements is FALSE regarding antigenicity?

Most antigens are proteins.
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Haptens illicit immune response on their own.
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Adjuvants enhance the immune response to antigen.
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. The binding site for an antigen is an epitope.
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Antigens induce an immune response by binding to antibody.
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Question 7 of 20

7. Question

An important granular leukocyte defense of the body against parasitic infection is mediated by:

Eosinophils
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Basophils
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Mast cells.
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PMNs.
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Dendritic cells.
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Question 8 of 20

8. Question

Each of the following cell types is an antigen presenting cell (APC) that presents antigen via MHC II proteins EXCEPT:

Monocytes
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B cells.
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Macrophages
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Langerhans cells.
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PMNs.
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Question 9 of 20

9. Question

A 3-year-old child presents with deformation of the ear and lip, cardiac malformation (of the aortic arch), and defective immune defense due to thymic hypoplasia. Which disorder is suspected?

Common variable immunodeficiency
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Wiskott-Aldrich syndrome
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SCID (severe combined immunodeficiency)
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Bruton X-linked agammaglobulinemia
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DiGeorge syndrome
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Question 10 of 20

10. Question

Each of the following immunodeficiencies presents with a defect in B cell function EXCEPT:

Bruton X-linked agammaglobulinemia
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Wiskott-Aldrich syndrome
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Isolated IgA deficiency.
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Job syndrome.
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Ataxia telangiectasia.
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Question 11 of 20

11. Question

Each of the following clinical or pathological findings is seen with DiGeorge syndrome EXCEPT:

Hypercalcemia
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Thymic hypoplasia.
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Microdeletion of chromosome 22.
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Palatal clefting.
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T-cell defects.
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Question 12 of 20

12. Question

Which of the following is TRUE of a type IV hypersensitivity reaction?

It is mediated by B cells.
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It is an immediate response.
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It involves the binding of class II MHC to a TCR.
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An example of this reaction is seen with hemolytic anemia.
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An example of this reaction is seen with atopic allergy.
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Question 13 of 20

13. Question

Which type of tissue graft involves the transplantation of tissue between two genetically different individuals within the same species?

Xenograft
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Allograft
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Autograft
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Isograft
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None of the above
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Question 14 of 20

14. Question

Which immunoglobulin can readily cross the placental barrier and function in passive immunity for the fetus?

IgA
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IgG
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IgD
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IgE
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IgM
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Question 15 of 20

15. Question

Immunoglobulin A (IgA) is secreted via exocrine glands and performs which primary function?

Mediates type I hypersensitivity.
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Activates complement.
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Its response is uncertain.
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Is the main antimicrobial defense of the primary response.
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Prevents mucosal membrane attachment of microbes.
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Question 16 of 20

16. Question

Each of the following is true of an antibody’s general structure EXCEPT:

Activation of complement via the alternative pathway.
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Its Fab regions determine the idiotype.
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Its Fc regions determine the isotype.
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The constant regions bind APC or C3b.
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The variable regions bind specific antigen.
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Question 17 of 20

17. Question

Which syndrome is defined by Trisomy 18, characterized by mental retardation, micrognathia, pinched facial appearance, and malformed ears?

Patau syndrome
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Klinefelter syndrome
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Down syndrome
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Turner syndrome
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Edward syndrome
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Question 18 of 20

18. Question

Regarding pathological development, which agent is NOT part of the TORCH complex and is NOT considered teratogenic?

Cytomegalovirus
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Rubella
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Toxoplasmosis
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Herpes simplex virus
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Influenza
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Question 19 of 20

19. Question

Which of the following is TRUE of impetigo?

It is noncontagious.
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It primarily affects the elderly.
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It is caused by Staphylococcus aureus or Streptococcus pyogenes infection.
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. It invades deep into the skin structure.
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It has a very low cure rate.
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Question 20 of 20

20. Question

Each of the following is commonly found in patients afflicted with cystic fibrosis (CF) EXCEPT:

Malfunction of the $\text{Cl}^-$ transporter.
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Meconium ileus.
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Pathology of chromosome 9.
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Pancreatic exocrine insufficiency.
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Bronchiectasis.
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Microbiology and Pathology Quiz 10

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